Fig. 10 | Scientific Reports

Fig. 10

From: Integrated network pharmacology, transcriptomics, and experimental validation to explore the mechanism of Qihuang Jianpi Zishen granules against Sjögren’s syndrome

Fig. 10

QJZG reduces IFN-γ-induced apoptosis in HSG cells. (A-B) mRNA expression levels of Bcl-2 and Bax in IFN-γ-induced HSG cells, measured by RT-qPCR (n = 3). (C) Fluorescence of HSG cell apoptosis detected by Annexin V/PI assay following treatment with IFN-γ alone or in combination with QJZG/TGP, where green fluorescence marks early apoptotic cells and red fluorescence marks late apoptotic cells. Statistical significance between groups is indicated by the following p-values: ***P < 0.001, **P < 0.01, *P < 0.05, nsP > 0.05.

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