Table 5 Comparison of the catalytic activity of Fe–N–C/DDQ catalyst system in the oxidation of diethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate with some reported procedures.

From: The single Fe atoms and DDQ catalyst system for the aerobic dehydrogenation of dihydropyridines and dihydroquinazolinones

Entry

Catalyst

Reaction conditions

Time (h)

Isolated yield (%)

References

1

NHPI (10 mol%)/Co(OAC)2 (0.5 mol%)

CH3CN, O2, Reflux

4 h

99

74

2

Laccase (200 U)/4-phenyl urazole (20 mol%)

NaPBS/CH3CN,O2, 40 °C

22 h

99

75

3

Laccase (168 U)/ABTS (10 mol%)

Acetate buffer/MeOH, air, 50 °C

9 h

80

103

4

AuCNT (10 mol%)/2,5-dichlorocyclohexa-2,5-diene-1,4-dione (200 mol%)

CHCl3/H2O

36 h

78

104

5

Fe–N–C (70 mg, 4.3 mol% of Fe), DDQ (10 mol%), O2 (balloon)

H2O/MeCN, R. T

6.51 h

94

This work