Table 7 Comparison of the catalytic performance of the Cu@ZIF-8 with the earlier reported catalysts for the and Biginelli reactions.

1

Cu@ZPD

EtOH, Reflux

⁸⁶

2

Zn-CurOAc Bio-MOF

EtOH, RT

⁵¹

3

Ni-DDIA(MOF)-(0.015 mmol)

Toluene, 75 °C

⁸⁷

4

MIL-101(Cr)–NH-CO-Pr-CO2H-(0.022 mmol)

Solvent-free, 100 °C

⁸⁸

5

Ni-DDIA(MOF)-(0.005 mmol)

Solvent-free, 80 °C

⁸⁷

6

0.2NbCl₅-BMImCl (5 mol%)

Solvent-free, 100 °C

⁸⁹

7

Cu (II)- MOF Derived via Transmetalation − (10 wt%)

Solvent-free, 60 °C

⁹⁰

8

Fe₃O₄/pectin/(Co/Cu) MOF

Solvent-free, 85 °C

⁹¹

9

PAA/ZIF-67

Solvent-free, 75 °C

⁹²

10

PTA@MIL-101 (0.006 mmol)

Solvent-free, 100 °C

⁹³

11

Cu@ZIF-8

EtOH, Reflux

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