Fig. 3
Histological evaluation of colonic damage and corresponding histology scores in DSS-induced colitis mice. (A) Representative hematoxylin and eosin (H&E) stained colon sections from each group: Sham, DSS-CON, DSS-LGG, DSS-CBA7104, DSS-CBA7106, DSS-CBA7108, and DSS-BBH. DSS treatment caused substantial epithelial disruption, crypt loss, and inflammatory cell infiltration, which were partially restored in probiotic-treated groups. Scale bars = 100 μm. (B) Quantitative histology scores based on epithelial integrity, crypt architecture, and inflammatory cell infiltration. Data are presented as mean ± SEM (n = 6 per group). Statistical significance was assessed using one-way ANOVA followed by Tukey’s post hoc test. p < 0.05, p < 0.01, p < 0.001.*p < .0001, vs. Sham; ***p < .001, ****p < .0001, vs. DSS-CON.
