Table 5 Associations of GWG patterns with PTB subtypes stratified by pre-pregnacy BMI in the adjusted model.
Variables | PTB | Spontaneous PTB | PPROM | Medically indicated PTB | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n (%) | Adjusted OR (95% CI) | P | n (%) | Adjusted OR (95% CI) | P | n (%) | Adjusted OR (95% CI) | P | n (%) | Adjusted OR (95% CI) | P | ||
Total GWG in the first and second trimesters | |||||||||||||
Underweight (< 18.5 kg/m2) | Insufficient | 31 (2.7) | 1.27 (0.82–1.97) | 0.281 | 12 (1.1) | 1.51 (0.73–3.10) | 0.263 | 5 (0.4) | 0.72 (0.27–1.96) | 0.523 | 14 (1.2) | 1.47 (0.76–2.85) | 0.258 |
Adequate | 61 (2.2) | 1.00 (Reference) | - | 20 (0.7) | 1.00 (Reference) | - | 17 (0.6) | 1.00 (Reference) | - | 24 (0.9) | 1.00 (Reference) | - | |
Excessive | 306 (4.7) | 2.19 (1.66–2.90) | < 0.001 | 97 (1.5) | 2.18 (1.34–3.54) | 0.002 | 86 (1.3) | 2.17 (1.29–3.66) | 0.004 | 123 (1.9) | 2.12 (1.37–3.30) | 0.001 | |
Normal (18.5–23.9 kg/m2) | Insufficient | 157 (5.4) | 2.09 (1.73–2.54) | < 0.001 | 46 (1.6) | 1.98 (1.40–2.79) | < 0.001 | 39 (1.3) | 1.66 (1.15–2.40) | 0.007 | 72 (2.5) | 2.43 (1.82–3.23) | < 0.001 |
Adequate | 374 (2.7) | 1.00 (Reference) | - | 113 (0.8) | 1.00 (Reference) | - | 114 (0.8) | 1.00 (Reference) | - | 147 (1.0) | 1.00 (Reference) | - | |
Excessive | 955 (3.6) | 1.35 (1.20–1.52) | < 0.001 | 265 (1.0) | 1.25 (1.00-1.56) | 0.048 | 271 (1.0) | 1.24 (0.99–1.54) | 0.059 | 419 (1.6) | 1.49 (1.24–1.81) | < 0.001 | |
Overweight/obesity (≥ 24 kg/m2) | Insufficient | 19 (8.3) | 2.43 (1.32–4.48) | 0.005 | 7 (3.1) | 3.75 (1.23–11.43) | 0.020 | 7 (3.1) | 3.80 (1.25–11.49) | 0.018 | 5 (2.2) | 1.12 (0.40–3.14) | 0.829 |
Adequate | 27 (3.9) | 1.00 (Reference) | - | 6 (0.9) | 1.00 (Reference) | - | 6 (0.9) | 1.00 (Reference) | - | 15 (2.1) | 1.00 (Reference) | - | |
Excessive | 69 (3.1) | 0.82 (0.52–1.29) | 0.381 | 11 (0.5) | 0.58 (0.21–1.58) | 0.287 | 22 (1.0) | 1.17 (0.47–2.90) | 0.739 | 36 (1.6) | 0.77 (0.42–1.42) | 0.408 | |
Average weekly eGWG (g/week) | |||||||||||||
Underweight (< 18.5 kg/m2) | Class I (< 100 g) | 29 (2.6) | 1.02 (0.68–1.52) | 0.931 | 9 (0.8) | 0.82 (0.41–1.66) | 0.582 | 9 (0.8) | 1.30 (0.63–2.69) | 0.475 | 11 (1.0) | 1.03 (0.54–1.97) | 0.919 |
Class II (100–399 g) | 173 (2.6) | 1.00 (Reference) | - | 65 (1.0) | 1.00 (Reference) | - | 41 (0.6) | 1.00 (Reference) | - | 67 (1.0) | 1.00 (Reference) | - | |
Class III (≥ 400 g) | 193 (8.2) | 3.31 (2.68–4.09) | < 0.001 | 54 (2.3) | 2.45 (1.70–3.53) | < 0.001 | 57 (2.4) | 3.97 (2.65–5.95) | < 0.001 | 82 (3.5) | 3.39 (1.44–4.70) | < 0.001 | |
Normal (18.5–23.9 kg/m2) | Class I (< 100 g) | 313 (4.8) | 1.84 (1.61–2.10) | < 0.001 | 97 (1.5) | 1.80 (1.42–2.28) | < 0.001 | 87 (1.3) | 1.86 (1.45–2.39) | < 0.001 | 129 (2.0) | 1.78 (1.45–2.18) | < 0.001 |
Class II (100–399 g) | 794 (2.7) | 1.00 (Reference) | - | 242 (0.8) | 1.00 (Reference) | - | 213 (0.7) | 1.00 (Reference) | - | 339 (1.2) | 1.00 (Reference) | - | |
Class III (≥ 400 g) | 337 (5.3) | 1.99 (1.75–2.27) | < 0.001 | 76 (1.2) | 1.47 (1.14–1.91) | 0.004 | 109 (1.7) | 2.34 (1.85–2.95) | < 0.001 | 152 (2.4) | 2.05 (1.69–2.49) | < 0.001 | |
Overweight/obesity (≥ 24 kg/m2) | Class I (< 100 g) | 37 (4.7) | 1.30 (0.86–1.97) | 0.208 | 10 (1.3) | 1.94 (0.83–4.53) | 0.127 | 12 (1.5) | 1.44 (0.70–2.97) | 0.320 | 15 (1.9) | 1.00 (0.54–1.84) | 0.990 |
Class II (100–399 g) | 68 (3.6) | 1.00 (Reference) | - | 12 (0.6) | 1.00 (Reference) | - | 20 (1.1) | 1.00 (Reference) | - | 36 (1.9) | 1.00 (Reference) | - | |
Class III (≥ 400 g) | 10 (2.7) | 0.75 (0.38–1.47) | 0.394 | 2 (0.5) | 0.86 (0.19–3.89) | 0.848 | 3 (0.8) | 0.73 (0.21–2.46) | 0.605 | 5 (1.3) | 0.73 (0.28–1.88) | 0.516 | |
