Fig. 1 | Scientific Reports

Fig. 1

From: Strictosamide and mitraphylline inhibit cancer cell motility by suppressing epithelial-mesenchymal transition via integrin α4-mediated signaling

Fig. 1

Bioactivity screening and chemical investigation of U. scandens. (A) Representative images showing each insert in the invasion assay and the relative number of invaded cells. AGS cells were treated with fractions (5 µg/mL; with 0.1% DMSO) for 24 h. Data represent mean ± S.D. * p < 0.05; ** p < 0.01. (B) Chemical structures of the eight isolated compounds 1–8. (C) The LC-MS base peak ion (BPI) chromatogram of the alkaloid-rich fraction of U. scandens. The isolated compounds are denoted on the corresponding chromatographic peaks. Notably, the intensities of chromatographic peaks do not represent absolute quantity of each compound because the MS signal intensity is heavily affected by ionization efficiency of each molecule.

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