Fig. 5 | Scientific Reports

Fig. 5

From: Electroconvulsive therapy improves distal colonic motility via the subdiaphragmatic vagus nerve in depressive-like mice

Fig. 5

Vagotomy blocks the improvement of colon motility disorder by ECS in mice. Note: (A) Schematic representation of the experimental procedure for chronic restraint stress (CRS) mice subjected to subdiaphragmatic vagotomy (sdVx) and Electroconvulsive Shock (ECS), followed by subsequent gastrointestinal (GI) motility tests. (B) Images of the stomach in the sham and vagotomy groups. (C) Bead latency test to measure colon transit time. Data are presented as mean ± SEM. Statistical analysis was performed using one-way ANOVA followed by appropriate post hoc tests (Tukey’s multiple comparisons test) to assess differences among groups, n = 10. *p < 0.05; **p < 0.01; ***p < 0.001.

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