Table 2 P values for FCs for each NRTIs in NL4-3 versus GX002 with the same DRMs.

From: In vitro comparison of the susceptibilities of the same drug resistance mutations to reverse-transcriptase inhibitors of subtype B and CRF01_AE HIV-1 strains

DRMs

NRTIs

AZT

3TC

TDF

FNC

ABC

FTC

M41L

0.0002

0.0209

0.0026

0.0016

0.01

0.2647

K65R

0.8534a

0.0013b

0.0216.c

0.0002

0.087

0.0101

D67N

0.8452

0.0172

0.8886

0.0109

0.9056

0.5877

M184V

0.8671

–

0.1053

0.0216

0.2795

–

T215Y

0.1047

0.0104

0.0026

0.0021

0.0023

0.5994

  1. aBold and Italics in the table indicates that there was no significant difference in FC between NL4-3 and GX002 for that drug in the presence of that drug resistance mutation(DRM), NRTIs: nucleoside reverse transcriptase inhibitors; bBold indicates that GX002 had a significantly higher FC than NL4-3; cItalics indicates that GX002 had a significantly lower FC than NL4-3.
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