Table 4 Sensitivity analyses, hazard ratios of all-cause mortality by ECW/TBW.

From: Non-linear association between extracellular water/total body water ratio and all-cause mortality: a population-based cohort study

Variable

Number of deaths/total

Non _ adjusted model

Model 1a

Model 2b

Model 3c

HR (95% CI)

P_value

HR (95% CI)

P_value

HR (95% CI)

P_value

HR (95% CI)

P_value

All-cause mortality excluding deaths that occurred within 2 years of follow-up

 ECW/TBW (%)

290/6321

1.04 (0.99–1.10)

0.110

1.08 (1.02–1.14)

0.009

1.07 (1.01–1.12)

0.014

1.05 (1.01–1.10)

0.022

ECW/TBW (Quartiles)

 ECW/TBW < 44.6

207/4744

1 (Ref)

 

1 (Ref)

 

1 (Ref)

 

1 (Ref)

 

 ECW/TBW ≥ 44.6

83/1577

1.32 (0.96–1.81)

0.083

1.76 (1.22–2.53)

0.002

1.65 (1.16–2.35)

0.006

1.65 (1.17–2.32)

0.005

All-cause mortality excluding participants who had cancer

 ECW/TBW (%)

293/6223

1.04 (0.99–1.10)

0.146

1.07 (1.01–1.14)

0.019

1.06 (1.00, 1.12)

0.037

1.05 (1.00–1.10)

0.024

ECW/TBW (Quartiles)

 ECW/TBW < 44.6

210/4753

1 (Ref)

 

1 (Ref)

 

1 (Ref)

 

1 (Ref)

 

 ECW/TBW ≥ 44.6

83/1585

1.35 (0.97–1.89)

0.078

1.78 (1.23–2.59)

0.002

1.64 (1.14–2.37)

0.008

1.68 (1.17–2.41)

0.005

  1. HR, hazard ratio; CI, confidence interval.
  2. aAdjusted for age, sex, marital status, race/ethnicity, education level, family income, and NHANES cycle.
  3. bFurther adjusted for smoking status, alcohol drinking status and physical activity.
  4. cFurther adjusted for hypertension, diabetes, coronary heart disease, BMI, creatinine, CRP, and albumin.