Table 1 Histological scoring system for intervertebral disc degeneration.
Categories | Descriptions |
|---|---|
Morphology of the NP | |
0 | The NP constitutes > 75% of the disc area |
1 | The NP constitutes 50–75% of the disc area |
2 | The NP constitutes 25–50% of the disc area |
3 | The NP constitutes < 25% of the disc area |
Cellularity of the NP | |
0 | Stellar-shaped cells with a proteoglycan matrix located at the periphery |
1 | Mostly stellar-shaped cells and partially round cells |
2 | Mostly round cells, separated by dense areas of proteoglycan matrix |
3 | Round cells, separated by dense areas of proteoglycan matrix |
Morphology of the AF | |
0 | Well-organized collagen lamellae without ruptures |
1 | Inward bulging, ruptured, or serpentine fibers constitute < 25% of the AF |
2 | Inward bulging, ruptured, or serpentine fibers constitute 25 − 50% of the AF |
3 | Inward bulging, ruptured, or serpentine fibers constitute > 50% of the AF |
Cellularity of the AF | |
0 | Fibroblasts comprise > 90% of the cells |
1 | Fibroblasts comprise > 75–90% of the cells |
2 | Intermediate |
3 | Chondrocytes comprise > 75% of the cells |
Border between the NP and AF | |
0 | Normal, without any interruption |
1 | Minimal interruption |
2 | Moderate interruption |
3 | Severe interruption |
