Fig. 4 | Scientific Reports

Fig. 4

From: A tryptophol-containing emulgel ameliorates imiquimod-induced mice psoriasis

Fig. 4

TOH-containing emulgel reduced mast cell infiltration in IMQ-induced psoriatic mice. (a) Representative images of Giemsa-stained dorsal skin from all groups of mice. Representative images of skin sections were taken at ×10 magnification (scale bars: 100 μm), and inset images were taken at ×40 magnification (scale bars: 50 μm). (b) Quantification of mast cell accumulation in the dorsal skin of the mice in all the groups (n = 8). (c) The mRNA expression levels of IL-33 were measured via RT-qPCR (n = 4). (d) Cytokine expression levels of IL-33 in the dorsal skin of mice in all groups were measured using ELISA (n = 5). (e) The mRNA expression levels of ST2 were measured via RT-qPCR (n = 4). All the data are presented as the means ± SD. Statistical significance was determined by one-way ANOVA. *p < 0.05, **p < 0.01, and ***p < 0.001.

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