Table 4 Mediation analysis of AIP in the association between eGDR and MAFLD.

From: Association between estimated glucose disposal rate and the risk of MAFLD in American adults: a cross-sectional study

Independent

variable

Mediator

Total effect

Indirect effect

Direct effect

Proportion

mediated

Coefficient

(95% CI)

P

Coefficient (95% CI)

P

Coefficient (95% CI)

P

eGDR

AIP

āˆ’ā€‰0.0237(āˆ’ā€‰0.0280, āˆ’ā€‰0.0167)

ā€‰<ā€‰0.001

āˆ’ā€‰0.0021(āˆ’ā€‰0.0031, āˆ’ā€‰0.0010)

ā€‰<ā€‰0.001

āˆ’ā€‰0.0216(āˆ’ā€‰0.0262, āˆ’ā€‰0.0143)

ā€‰<ā€‰0.001

8.75%

  1. Adjusted for age, sex, race, education, PIR, marital status, BMI, AST, GGT, ALT, TC, TBIL, ALP, albumin, creatinine, uric acid, drinking, smoking, diabetes, hyperlipidemia, use of sex hormones, use of steroid medications and use of antidepressants.
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