Fig. 1
From: SMARCB1 orchestrates cellular plasticity and oncogenic pathways in typical and chondroid chordomas
Histopathological features and survival analysis of typical and chondroid chordomas. (A–D) Representative hematoxylin and eosin (H&E) stained sections of typical (A, C) and chondroid (B, D) chordomas. (A, C) Typical chordoma showing a lobulated architecture with characteristic physaliphorous cells embedded in a myxoid stroma. (B, D) Chondroid chordoma displaying areas of cartilaginous differentiation interspersed with typical chordoma features. Scale bars: 250 µm (A, B) and 50 µm (C, D). (E, F) Kaplan–Meier survival curves comparing typical (blue) and chondroid (red) chordoma subtypes. (E) Progression-free survival (PFS) and (F) overall survival (OS) analyses. Dotted lines represent 95% confidence intervals. Median PFS: 120 months (typical) versus 109 months (chondroid), P = 0.605. Median OS: 120 months (typical) versus 118 months (chondroid), P = 0.652. n = 26 typical and 16 chondroid chordomas.
