Table 2 Factors associated with Romosozumab nonadherence.

From: Risk factors and reasons for romosozumab nonadherence in a case-control study

 

Crude OR

95% CI

p-value

Adjusted OR

95% CI

p-value

Age at first treatment

 < 60 years

Ref.

  

Ref.

  

 60–69 years

1.733

0.443–6.789

0.430

1.833

0.435–7.717

0.409

 70–79 years

2.489

0.703–8.814

0.158

3.287

0.812–13.3

0.095

 ≥ 80 years

1.533

0.437–5.38

0.504

2.511

0.612–10.298

0.201

Sex

 Female

Ref.

  

Ref.

  

 Male

14.161

1.794-111.778

0.012

9.03

1.093–74.581

0.041

Romosozumab expenses

 Full subsidy

Ref.

  

Ref.

  

 Self-payment

2.777

1.297–5.945

0.009

2.756

1.14–6.663

0.024

Fracture history

 None

Ref.

  

Ref.

  

 Within 1 year before treatment

0.557

0.242–1.286

0.170

0.614

0.213–1.773

0.368

History of orthopedic surgery

 None

Ref.

  

Ref.

  

 Within 1 year before treatment

0.949

0.462–1.953

0.888

1.312

0.51–3.375

0.574

 During treatment

1.600

0.428–5.982

0.485

1.302

0.284–5.965

0.734

  1. The model was adjusted for age, sex, type of payment for romosozumab therapy, history of fracture, and history of orthopedic surgery.