Fig. 1

RNF126 expression is upregulated in PCa tissues and correlated with poor prognosis. A RNF126 levels in PCa tissues and normal prostate tissues from TCGA-PRAD dataset. B GEO profiling of RNF126 levels in PCa tissues and normal prostate tissues extracted from GEO dataset GDS4824. C A western blot showed the relative expression of RNF126 protein in 6 PCa tissues compared with adjacent non-cancerous normal tissues. D A qRT-PCR result showed the relative expression of RNF126 mRNA in 6 PCa tissues compared with adjacent non-cancerous normal tissues. E IHC staining of RNF126 was performed in 8 in PCa tissues and 8 normal prostate tissues (bar, 50 μm, left panel). Comparative analysis of RNF126 expression among PCa tissues and normal prostate tissues was shown (right panel). F The relationship between RNF126 levels and the prognosis of PCa patients based on TCGA-PRAD database. The data are shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.