Fig. 6 | Scientific Reports

Fig. 6

From: Immune transcriptomic analysis on COVID-19 patients with varying clinical presentations identifies severity markers

Fig. 6The alternative text for this image may have been generated using AI.

Co-expression gene modules present in blood transcriptomes of COVID‐19 patients. (A) Bubble heatmap showing the results of gene set enrichment analysis, indicating the module (M) activity in COVID‐19 patients. Circle size and color reflect the normalized enrichment score (NES), as determined by CEMiTool. (B) Enriched modules contain hubs genes. (C) Interaction plot for M1, (D) M2, (E) M5 and (F) M6, which contains genes enriching different immunity‐associated pathways, exhibited by the GO BP and KEGG pathway bar plot at the right side of Fig. C-F. The most connected genes (hubs) are highlighted inside rectangles. The node size is proportional to its degree of interactivity. The bar plot indicates the top 10 enriched pathways from the over‐representation analysis of module M1: C, M2: D, M5: E and M6: F.

Back to article page