Table 2 Top-ranked transcripts based on partial least-square discriminant analysis (PLS-DA) (Top 30 transcripts, VIP ≥ 1.3).

From: Immune transcriptomic analysis on COVID-19 patients with varying clinical presentations identifies severity markers

Gene name

Gene description (Homo sapiens)

Comp 1

Comp 2

Literature

IL10RA

Interleukin 10 receptor subunit alpha

0.4077

0

29,30

TRIM44

Tripartite motif containing 44

0.35684

0

31

PRKCH

Protein kinase C eta

0.3429

0

32,33

MAPRE2

Microtubule associated protein RP/EB family member 2

0.33651

0

34

ARL4 C

ADP ribosylation factor like GTPase 4 C

0.32898

0

 

PEA15

Proliferation and apoptosis adaptor protein 15

0.208

0

35

FYN

FYN proto-oncogene, Src family tyrosine kinase

0.18817

0

36

NFATC2

Nuclear factor of activated T cells 2

0.18049

0

37,38

SLC22 A4

Solute carrier family 22 member 4

−0.17414

0

39,40

TMEM109

Transmembrane protein 109

0.16776

0

 

RFTN1

Raftlin, lipid raft linker 1

0.16662

0

41

CD4

CD4 molecule

0.15735

0

42

GATA3

GATA binding protein 3

0.14565

0

43

RNF125

Ring finger protein 125

0.14514

0

44

PRKX

Protein kinase cAMP-dependent X-linked catalytic subunit

0.14018

0

 

TSPYL1

TSPY like 1

0.13007

0

 

SMAD3

SMAD family member 3

0.11737

0

 

EVL

Enah/Vasp-like

0.10846

0

 

SIDT1

SID1 transmembrane family member 1

0.091469

0

45,46

PRKCQ

Protein kinase C theta

0.083045

0

47

ANKRD40

Ankyrin repeat domain 40

0.078975

0

48

RRP1B

Ribosomal RNA processing 1B

0.077167

0

 

TMEM11

Transmembrane protein 11

−0.07035

0

 

KDM2B

Lysine demethylase 2B

0.066945

0

 

TSHZ1

Teashirt zinc finger homeobox 1

0.047419

0

 

TIAM1

TIAM Rac1 associated GEF 1

0.024474

0

49

CX3 CR1

C-X3-C motif chemokine receptor 1

0.022411

0

50

TXN

Thioredoxin

−0.01567

0

51

CD247

CD247 molecule

0.015149

0

52

RASA3

RAS p21 protein activator 3

0.008574

0

53

Back to article page