Table 1 Characterization of patients with AN.

From: Identification of autoantibodies against HIF1a in patients with anorexia nervosa and their potential role in hepatic cytolysis

Patients

Age

Gender

Subgroup

Onset

BMI (Body mass index)

Biochemical panel

Liver function panel

Immunological panel

Proteins (g/L)

Albumin (g/L)

Aspartate aminotransferase (AST) (UI/ml)

Alanine aminotransferase (ALT) (UI/ml)

Hepatic cytolysis (ALT) (UI/ml) (> 2xNV)

Antinuclear autoantibodies (ANA)

Autoantibodies related to liver autoimmune disease (AL)

A

15

F

Restrictive

2022

15.6

61.7

40.6

34

68

No

Negative

Negative

B

22

F

Restrictive

2017

12.2

71.6

39.6

20

27

No

Negative

Negative

C

13

F

Purgative

2020

14.1

79.8

15

14

No

S

Negative

D

15

F

Restrictive

2021

15

75.9

42.7

26

32

No

Negative

Negative

E

8

M

Restrictive

2022

14.7

76.5

39.9

17

9

No

S

Negative

F

56

F

Restrictive

1990

14.4

72.7

32.7

18

14

No

Negative

Negative

G

14

F

Restrictive

2021

18

79.2

39

23

26

No

Negative

Negative

H

17

F

Restrictive

2022

14.2

75.9

39.2

35

15

No

Negative

Negative

I

20

F

Restrictive

2020

18.6

70

215

Yes

VS

Negative**

J

17

F

Restrictive

2021

12.3

66.9

44.3

17

75

No

Negative

Negative

K

15

F

Restrictive

2022

10.1

66

38.9

85

220

Yes

VS

Negative**

L

48

F

Purgative

1990

11.5

78.2

43.1

55

54

No

Negative

Negative

M

15

F

Restrictive

2021

11.9

70

 < 8

 < 9

No

Negative

Negative

N

33

F

Restrictive

2011

17

53.3

19.1

339

433

Yes

Negative

Negative

O

21

F

Restrictive

2018

10.6

56.9

33.4

115

372

Yes

Négative

Negative

P

25

F

Restrictive

2020

15.1

74.3

63.4

31

140

Yes

Negative

Negative

Q

17

F

Restrictive

2020

13.7

72.1

43.8

13

22

No

Negative

Negative

R

22

F

Purgative

2020

15.2

62.5

32.8

31

53

No

Negative

Negative

  1. VS: variable speckled immunofluorescence intensity; S: speckled immunofluorescence intensity.
  2. **a graduated labelling of renal sections, with an occasional nuclear labelling of cortical tubules contrasting with a nuclear labelling on the whole medullar tubules.
  3. –: missing data, no information was available or could be collected during the data collection process.
  4. Normal value (NV): AST: > 40; ALT: > 45; Albumin: 34–50 g/L; Protéins: 57–82 g/L.