Fig. 3 | Scientific Reports

Fig. 3

From: HIIT and MICT mitigate endothelial dysfunction in early atherosclerotic mice via PCSK9 inhibition

Fig. 3

MICT and HIIT inhibit the TRX/TXNIP/NLRP3/GSDMD-N signaling pathway in the aortas of atherosclerotic mice. (A and B) The protein expressions of TRX/TXNIP and NLRP3/GSDMD-N were detected by western blot. (C and D) Immunohistochemical staining was performed to detect NLRP3 and GSDMD-N in the aortas. *P < 0.05, AS-S compared with Control; #P < 0.05, AS-MICT and AS-HIIT compared with AS-S. Data are presented as means ± SD.

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