Fig. 4

Western blot validations confirm the upregulation of complement C3 and apolipoprotein C4 in UC and SEC samples, respectively. (a) Representative western blot images of complement C3 and apolipoprotein C4 in an independent cohort of 6 donors from whom EVs were isolated by UC and SEC. Densitometry data for (b) complement C3 and (c) apolipoprotein C4. Western blot analysis was performed in N = 12; * p < 0.05.