Fig. 2

Spatial representation of the tooth and the lip stimulation in the TG. (a) Spatial maps of ΔF/F₀ during tooth stimulation (left) and lip stimulation (right) from the same imaging site. The scale bar, 200 µm. Top inset images are the mouse face with somatosensory stimulation sites as red dots. The scale bar, 2 mm. (b) Examples of fluorescent changes in two neurons indicated with arrows in panel a. The left two columns show individual traces overlaid for 10 trials, and the right column shows the average traces. (c) Top, Averaged sensory response of tooth selective neurons and lip selective neurons. Black: tooth selective neurons (n = 84), gray: lip selective neurons (n = 72). Note that non-selective neurons are excluded. Bottom, the cumulative distributions of half rise times and half decay times. (d) ∆F/F₀ traces for 69 neurons in panel a showing the responses to tooth stimulation (left) and lip stimulation (right). The cells were sorted based on the difference in activity during tooth and lip stimulation. (e) Distribution of the selectivity index from all imaging sessions (n = 292 from 9 mice). (f) Map of the selectivity index. Each circle corresponds to a cell, and the gray tone of the cells indicates the selectivity index. Left, the map from the experiment shown in panel a. Right, the map from all 9 mice (n = 292). There was no segregation between tooth-selective cells and lip-selective cells. (g) The relationship between the center of gravity for the tooth response and that for the lip response for 9 mice. There was no clear.