Table 2 Multivariate competing risk analysis of postoperative CSS in elderly patients with stage I–III CRC.
Overall survival | All | HR (Competing risks multivariable) | |
|---|---|---|---|
Age | 65–74 years | 6350 (47.3%) | |
75–84 years | 4959 (36.9%) | 1.35 (1.24–1.46 p < 0.001) | |
85 + years | 2127 (15.8%) | 1.70 (1.52–1.90 p < 0.001) | |
Sex | Female | 7071 (52.6%) | |
Male | 6365 (47.4%) | ||
Race | Black | 1198 (8.9%) | |
Other | 1308 (9.7%) | 0.81 (0.69–0.96 p = 0.014) | |
White | 10930 (81.3%) | 0.86 (0.76–0.98 p = 0.022) | |
Marital | Married | 7120 (53.0%) | |
Unmarried | 6316 (47.0%) | 1.12 (1.03–1.21 p = 0.005) | |
Site | Colon | 10874 (80.9%) | |
Rectum | 2562 (19.1%) | 1.37 (1.25–1.50 p < 0.001) | |
Histology | Adenocarcinoma | 12078 (89.9%) | |
Other | 1358 (10.1%) | 1.07 (0.95–1.20 p = 0.240) | |
Grade | I | 982 (7.3%) | |
II | 9784 (72.8%) | 1.15 (0.96–1.38 p = 0.120) | |
III | 2219 (16.5%) | 1.26 (1.04–1.53 p = 0.019) | |
IV | 451 (3.4%) | 1.47 (1.14–1.89 p = 0.003) | |
T | T1 | 1300 (9.7%) | |
T2 | 2384 (17.7%) | 1.36 (1.05–1.77 p = 0.022) | |
T3 | 7820 (58.2%) | 2.57 (2.02–3.26 p < 0.001) | |
T4 | 1932 (14.4%) | 5.09 (3.97–6.54 p < 0.001) | |
N | N0 | 8422 (62.7%) | |
N1 | 3460 (25.8%) | 1.87 (1.71–2.05 p < 0.001) | |
N2 | 1554 (11.6%) | 3.12 (2.80–3.47 p < 0.001) | |
CEA | Negative | 8347 (62.1%) | |
Positive | 5089 (37.9%) | 1.41 (1.31–1.52 p < 0.001) | |
Deposits | No | 12144 (90.4%) | |
Yes | 1292 (9.6%) | 1.43 (1.29–1.58 p < 0.001) | |
Invasion | No | 12168 (90.6%) | |
Yes | 1268 (9.4%) | 1.40 (1.27–1.56 p < 0.001) | |
Size | < 5 cm | 7938 (59.1%) | |
≥ 5 cm | 5498 (40.9%) | 1.06 (0.98–1.15 p = 0.130) | |
