Fig. 2 | Scientific Reports

Fig. 2

From: Integrated bioinformatics analysis identifies CHAD association with osteoporosis and in vitro chondrogenic effects of Wogonin

Fig. 2

Single Cell RNA Sequence Analysis. Umap visualization separate by normal and osteoporosis groups before and after CCA integration (A). Umap visualization with cell clusters annotation and dotplot (B,C). Cell type composition graph showed erythrocytes and adipocytes upregulated in osteoporosis groups. However, macrophage and neutrophil downregulated (D). Differential gene expressions analysis in stromal cell showed 5 common genes compared with previous Bulk RNA Sequence results (E). Gene expressions of 5 common genes, including CHAD, ACAN, COL2A1, HAPLN1, FKBP5 (F).

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