Table 6 Study characteristics.

From: Influence of wearable rhythmic auditory stimulation on Parkinson’s disease, multiple sclerosis, and stroke: a systematic review and meta-analysis

Author (year)

Study design

Sample size

(dropouts)

Mean age

♂/♀

Intervention

duration

RAS

Wearable

device(s)

Outcome

Baram et al. (2007)46

non-RCT

14 MS + 11 healthy

48.6 25.5

4/10

5/6

1 session

adaptive

headphones

sensor

gait parameters

Calvano et al (2023)28

RCT

25 PD

61.0

15/10

2 sessions in 2 days

fixed-tempo

headphones

sensors

MP3-player

motor function

Chomiak et al (2017)40

non-RCT (pilot)

11 PD

69.9

9/2

3x/w, 10–20’, 4w

fixed-tempo

headphones

sensors

step automaticity

clinical test(s)/ questionnaire(s)

Cochen De Cock et al. (2021)47

non-RCT

45 (6) PD

65.0

15/20

5x/w, 30’, 4w

adaptive

BeatWalk

smartphone application

headphones

sensors

gait parameters

clinical test(s)/ questionnaire(s)

Collimore et al. (2023)44

non-RCT

10 chronic stroke

60.2

7/3

1 session

adaptive

headphones

sensors

gait asymmetry

Conklyn et al (2010)29

RCT (pilot)

10 MS

48.6

3/7

7x/w, 20’, 2 or 4w

fixed-tempo

headphones

MP3-player

gait parameters

De Bartolo et al (2020)48

non-RCT

20 PD

72.5

14/6

1 session

fixed-tempo

headphones

sensor

gait parameters

Elsner et al (2020)30

RCT (pilot)

12 chronic stroke

67.0

3/9

3x/w, 30’, 4w

fixed-tempo

headphones

MP3-player

gait parameters

clinical test(s)/ questionnaire(s)

Erra et al (2019)49

non-RCT

30 PD

72.0

20/10

1 session

fixed-tempo

headphones

sensors

gait parameters

Ginis et al (2017)41

non-RCT

28 PD

62.0

23/5

1 session

2 conditions adaptive

1 condition fixed-tempo

headphones

sensors

gait deviations

Ginis et al (2017)42

non-RCT

28 PD + 13 healthy

62.0

60.2

23/5

7/6

1 session

2 conditions adaptive

1 condition fixed-tempo

headphones

sensors

gait parameters

Guimarães et al (2015)51

non-RCT

12 PD

71.2

7/5

1 session

fixed-tempo

headphones

gait parameters

Hove et al (2012)52

non-RCT

20 PD + 18 healthy

69.2

24.7

8/12

16/2

1 session

1 condition adaptive

1 condition fixed-tempo

WalkMate

headphones

sensors

fractal scaling

Hutchinson et al (2020)45

non-RCT

11 chronic stroke

57.7

9/2

1 or 3 session(s)

in 1 or 3 days

adaptive

headphones

sensors

gait parameters

Kim et al (2012)31

RCT

18 (2) subacute stroke

55.1

13/7

3x/w, 30’, 5w

fixed-tempo

earphones

gait parameters

clinical test(s)/ questionnaire(s)

Li et al (2022)32

RCT

40 PD

63.8

34/36

5x/w, 1h, 4w

fixed-tempo

headphones

music player

gait parameters

clinical test(s)/ questionnaire(s)

Lopez et al (2014)54

non-RCT

10 PD

55.0

7/3

1 session

fixed-tempo

Listenmee®

smartphone application

headphones

glasses

smartwatch

gait parameters

Mainka et al (2018)33

RCT

45 (10) stroke

63.4

26/9

5x/w, 15’-20’, 4w

fixed-tempo

earplugs

MP3-player

gait parameters

clinical test(s)/ questionnaire(s)

Moumdjian et al (2019)43

non-RCT

31 (4) MS + 30 (2) healthy

53.5

51.8

8/23

8/22

1 session

adaptive

D-Jogger

headphones

music player

sensors

gait parameters

Murgia et al (2018)34

RCT

38 (6) PD

68.2

/

2x/w, 45’, 5w + train 3x/w at home

fixed-tempo

headphones

MP3-player

gait parameters

clinical test(s)/ questionnaire(s)

Nieuwboer et al (2009)50

non-RCT

133 PD

66.6

78/55

1 session

fixed-tempo

earphone

sensors

functional turning performance

Park et al (2015)35

RCT (pilot)

19 chronic stroke

53.4

10/9

5x/w, 30’, 3w

fixed-tempo

headphones

gait parameters

clinical test(s)/ questionnaire(s)

Park et al (2021)55

non-RCT

20 PD

68.9

13/7

2 sessions in 1 day

fixed-tempo

APDM system

headphones

sensors

gait parameters

arm swing

Park et al (2020)56

non-RCT

23 PD

69.5

15/8

1 session

fixed-tempo

APDM system

headphones

sensors

gait parameters

arm swing

Shahraki et al. (2017)36

RCT

18 MS

39.2

4/14

3x/w, 30’, 3w

fixed-tempo

headphones

gait parameters

Thaut et al (1996)37

RCT

37 PD

71.3

26/11

7x/w, 30’, 3w

fixed-tempo

headphones

music players

gait parameters

clinical test(s)/ questionnaire(s)

Thaut et al (2019)13

RCT

60 (13) PD

72.0

32/28

7x/w, 30’, 24w

fixed-tempo

headphones

MP3-player

sensors

gait parameters

clinical test(s)/ questionnaire(s)

Uchitomi et al (2016)53

non-RCT

30 PD + 18 healthy

74.9

70.6

16/14

12/6

1 session

adaptive

Walk-Mate

headphones

sensors

stride interval

Uchitomi et al (2013)38

RCT

32 PD

70.4

18/14

4 sessions

in 4 days

2 conditions fixed-tempo

1 condition adaptive

Walk-Mate

headphones

sensors

stride interval

Hutin et al (2024)39

RCT

15 PD

70

8/7

2 sessions

adaptive

headphones

smartphone applications

sensors

GAIT Tutor ®

gait parameters

clinical test(s)/ questionnaire(s)