Fig. 4 | Scientific Reports

Fig. 4

From: ADRB2 is regulated by TRIM22 and facilitates lung adenocarcinoma progression via JAK2/STAT3 signaling pathway

Fig. 4

Overexpression of ADRB2 activated JAK2/STAT3 signaling pathway. (A) The significant pathway activated in the high ADRB2 expression group via GSEA enrichment analysis. (B-D) Phosphorylation of JAK2 and STAT3 after overexpression of ADRB2 in A549 cells by western blot analysis. (E-G) Phosphorylation of JAK2 and STAT3 after downregulation of ADRB2 in H1299 cells by western blot analysis. *P <0.05 and ***P < 0.001.

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