Fig. 1
From: SRT2104 enhances dendritic outgrowth and spine formation through Sirtuin 1-mediated mTORC1 signaling
Effects of SRT2104 on cell viability in primary cortical cells. Cortical cells were treated with SRT2104 (0.1, 1, 10, and 50 µM) or DMSO (non-drug treated control, final concentration 1%) for 4 days in the presence or absence of dexamethasone (500 µM). An MTT assay was performed (n = 8). The values represent the mean ± SEM expressed as a percentage of the control cells (DMSO-treated, non-dexamethasone-treated cells). ***P < 0.001 vs. control cells; †††P < 0.001 vs. DMSO-treated, dexamethasone-treated cells.
