Fig. 4 | Scientific Reports

Fig. 4

From: SRT2104 enhances dendritic outgrowth and spine formation through Sirtuin 1-mediated mTORC1 signaling

Fig. 4

Effects of SRT2104 on the levels of PSD-95 and GluA1 expression in dexamethasone-treated cells. Cortical cells were treated with SRT2104 (0.1 and 1 µM) or DMSO for 4 days in the presence of dexamethasone. The levels of PSD-95 (A) and GluA1 (B) were determined by Western blotting (n = 6). Full-length uncropped gels for all Western blots are available in the Supplementary Information. The values represent the mean ± SEM expressed as a percentage of control cells (DMSO-treated, non-dexamethasone-treated cells). **P < 0.01 vs. control cells; P < 0.05 or ††P < 0.01 vs. DMSO-treated, dexamethasone-treated cells.

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