Table 1 Comparison of residues within 12Å of the copper ions on the pocket surfaces of mTYR and hTYR.
From: Theoretical studies of arbutin, glutathione, and sea cucumber extracts as inhibitors of tyrosinase
Amino acid type | Tyrosinase | Amino acid number |
|---|---|---|
Polar Amino Acids | hTYR | S165、S341、S356、N345、Q357、Q359 |
mTYR | N80、N259、C82、T83、T260、G85、S281 | |
Hydrophobic Amino Acids | hTYR | L260、F328、I349、V358 |
mTYR | F89、F263、M256、M279、V257、V282、P283、A285 | |
Acidic Amino Acids | hTYR | D167、D178、D180、D286、E184 |
mTYR | E255 | |
Basic Amino Acids | hTYR | R177、R289、K315 |
mTYR | H243、R267 |
