Table 1 Baseline attributes of all participants.
Variables | Total (N = 43853) | Non-Stroke (N = 42179) | Stroke (N = 1674) | P value |
|---|---|---|---|---|
Weighted Participants, n | 1764428353.05 | 1715838635.81 | 48589717.24 | NA |
EASIX, median, IQR | 0.45 (0.33–0.62) | 0.45 (0.33–0.61) | 0.60 (0.42–0.90) | < 0.001 |
Demographics | ||||
Age, years, median, IQR | 49 (34–64) | 48 (34–63) | 69 (60–78) | < 0.001 |
Gender, female, n (%) | 22,670 (51.7) | 21,822 (51.74) | 848 (50.66) | 0.39 |
Race/ethnicity, n (%) | < 0.001 | |||
Non-Hispanic white | 7646 (17.44) | 7458 (17.68) | 188 (11.23) | |
Non-Hispanic black | 3812 (8.69) | 3723 (8.83) | 89 (5.32) | |
Other Hispanic | 19,173 (43.72) | 18,307 (43.40) | 866 (51.73) | |
Mexican American | 8933 (20.37) | 8510 (20.18) | 423 (25.27) | |
Others | 4289 (9.78) | 4181 (9.91) | 108 (6.45) | |
Social indicators | ||||
Marital status, n (%) | < 0.001 | |||
Never married | 7599 (17.33) | 7465 (17.70) | 134 (8.00) | |
Married/living with partner | 26,150 (59.63) | 25,294 (59.97) | 856 (51.14) | |
Divorced/separated/widowed | 10,104 (23.04) | 9420 (22.33) | 684 (40.86) | |
Education, n (%) | ||||
Under high school | 11,741 (26.77) | 11,123 (26.37) | 618 (36.92) | < 0.001 |
High school or equivalent | 10,103 (23.04) | 9668 (22.92) | 435 (25.99) | |
Above high school | 22,009 (50.19) | 21,388 (50.71) | 621 (37.10) | |
Poverty-income ratio, median, IQR | 2.12 (1.12–4.07) | 2.15 (1.13–4.10) | 1.59 (1.02–2.82) | < 0.001 |
Health insurance status, n (%) | 34,492 (78.65) | 32,971 (78.17) | 1521 (90.86) | < 0.001 |
Health indicators | ||||
BMI, kg/m2, median, IQR | 28.0 (24.3–32.4) | 27.9 (24.3–32.4) | 28.8 (25.1-33.31) | < 0.001 |
Smoke status, n (%) | ||||
Never | 23,998 (54.72) | 23,318 (55.28) | 680 (40.62) | < 0.001 |
Current | 9028 (20.59) | 8648 (20.50) | 380 (22.70) | |
Former | 10,827 (24.69) | 10,213 (24.21) | 614 (36.68) | |
Alcohol use, n (%) | < 0.001 | |||
Never | 9248 (21.09) | 8861 (21.01) | 387 (23.12) | |
Mild | 7865 (17.93) | 7260 (17.21) | 605 (36.14) | |
Moderate | 13,113 (29.90) | 12,695 (30.10) | 418 (24.97) | |
Heavy | 5924 (13.51) | 5792 (13.73) | 132 (7.88) | |
Former | 7703 (17.57) | 7571 (17.95) | 132 (7.88) | |
SBP, mmHg, median, IQR | 122 (112–136) | 122 (112–134) | 134 (120–150) | < 0.001 |
DBP, mmHg, median, IQR | 70 (62–78) | 70 (64–78) | 70 (60–78) | < 0.001 |
Comorbidities | ||||
Hypertension, n (%) | 15,351 (35.01) | 14,088 (33.40) | 1263 (75.45) | < 0.001 |
Diabetes, n (%) | 5405 (12.33) | 4859 (11.52) | 546 (32.62) | < 0.001 |
Hyperlipidemia, n (%) | 31,897 (72.74) | 30,489 (72.28) | 1408 (84.11) | < 0.001 |
Liver condition, n (%) | 872 (1.99) | 794 (1.88) | 78 (4.66) | < 0.001 |
CHD, n (%) | 1822 (4.15) | 1519 (3.60) | 303 (18.10) | < 0.001 |
Myocardial infarction, n (%) | 1917 (4.37) | 1562 (3.70) | 355 (21.21) | < 0.001 |
Angina, n (%) | 1228 (2.80) | 1025 (2.43) | 203 (12.13) | < 0.001 |
CKD, n (%) | 1387 (3.16) | 1189 (2.82) | 198 (11.83) | < 0.001 |
CHF, n (%) | 1437 (3.28) | 1139 (2.70) | 298 (17.80) | < 0.001 |
Cancer, n (%) | 3955 (9.02) | 3614 (8.57) | 341 (20.37) | < 0.001 |
Laboratory parameters | ||||
PLT, 109/L, median, IQR | 243 (205–287) | 243 (206–287) | 231 (193–276) | < 0.001 |
Hemoglobin, g/dL, median, IQR | 14.1 (13.1–15.1) | 14.1 (13.1–15.2) | 13.7 (12.7–14.8) | < 0.001 |
eGFR, ml/min/1.73m2, median, IQR | 91.0 (75.5-109.3) | 91.8 (76.4-109.9) | 70.2 (54.8-88.03) | < 0.001 |
Total cholesterol, mg/dL, median, IQR | 192 (166–220) | 192 (166–220) | 183 (156–215) | < 0 0.001 |
HDL-C, mg/dL, median, IQR | 51 (42–62) | 51 (42–62) | 48 (40–60) | < 0.001 |
Non-HDL-C, mg/dL, median, IQR | 138 (112–167) | 138 (112–167) | 131 (103–163) | < 0.001 |
LDH, U/L, median, IQR | 131 (115–151) | 131 (114–150) | 140 (122–163) | < 0.001 |
Creatinine, mg/dL, median, IQR | 0.8 (0.7-1.0) | 0.8 (0.7-1.0) | 1.0 (0.8–1.2) | < 0.001 |
