Fig. 5 | Scientific Reports

Fig. 5

From: Correction: Exercise reduces hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice via its effects against inflammation and oxidative stress

Fig. 5

Effect of exercise on hyperlipidemia-induced cardiac oxidative stress. (A) GSH-Px and SOD levels in the four mouse groups after 12 weeks of different treatments. (B) Representative immunohistochemistry staining for NOX4, NRF2, and HO-1 in cardiac tissue of mice with different treatments. Scale bar = 100 μm. Arrows indicate positively stained cells. (C) NOX4, NRF2, and HO-1 positive cells. Data represent the mean ± SEM; n = 7 per group. (D) Western blotting for NOX4, NRF2. and HO-1 protein expression in cardiac tissue. (E) Quantification of NOX4, NRF2, and HO-1 protein expression. Data represent the mean ± SEM; n = 3 per group. *P < 0.05. GSH-Px glutathione peroxidase, SOD superoxide dismutase, HO-1 heme oxygenase 1, NRF2 nuclear factor erythroid 2-related factor, NOX4 NADPH Oxidase 4.

Back to article page