Fig. 4
The elevation of β-catenin expression normalized mitochondrial fission and fusion and hindered cardiomyocyte hypertrophy induced by homocysteine. (A) Western blot analyses showed the expressions of protein, including p-Drp1, Drp-1, Fis1, Mfn2, and OPA1 in indicated groups. (B–E) Quantitative determination of p-Drp1, Drp-1, Fis1, Mfn2, and OPA1 in (A). (F) Western blot analyses showed the expressions of protein, including α-actin, β-MHC in indicated groups. (G,H) Quantitative determination of α-actin, β-MHC in (F). (I) Rhodamine staining for cardiomyocytes revealed the cross-sectional area of the cells. (J) Quantitative determination of the cross-sectional area of cardiomyocytes. *P < 0.05 versus the controls; #P < 0.05 versus homocysteine stimulation alone (n = 6).
