Table 1 Echocardiographic measurements of mice in indicated group.

From: Homocysteine promotes cardiomyocyte hypertrophy through inhibiting β-catenin/ FUNDC1 mediated mitophagy

 

CTL

Hcy

Hcy + AAV-β-catenin

Hcy + AAV

IVSd (mm)

0.73 ± 0.02

0.94 ± 0.07*

0.79 ± 0.02#

0.95 ± 0.03

IVSs (mm)

1.05 ± 0.03

1.29 ± 0.06*

1.15 ± 0.02#

1.26 ± 0.04

HR (bpm)

574.75 ± 20.33

517.25 ± 17.84*

602.19 ± 22.68#

580.19 ± 15.24

LVIDs (mm)

2.57 ± 0.14

2.28 ± 0.05*

2.53 ± 0.05#

2.26 ± 0.04

LVIDd (mm)

3.65 ± 0.23

3.21 ± 0.11

3.56 ± 0.10

3.19 ± 0.04

LVESV (μl)

20.67 ± 1.12

17.73 ± 1.00*

20.63 ± 0.39#

17.31 ± 0.74

LVEDV (μl)

42.70 ± 0.70

36.53 ± 0.94*

42.05 ± 0.82#

36.55 ± 0.72

LVSV (μl)

22.02 ± 0.43

18.80 ± 1.01*

21.43 ± 0.50#

19.23 ± 0.16

LVEF (%)

54.91 ± 1.40

57.06 ± 1.56

56.85 ± 1.67

56.15 ± 2.94

LVFS (%)

31.54 ± 1.49

26.47 ± 0.90*

30.96 ± 1.03#

26.36 ± 0.88

CO (ml/min)

13.09 ± 0.41

9.76 ± 0.78*

12.43 ± 0.67#

11.83 ± 0.56

LVPWd (mm)

0.73 ± 0.04

0.82 ± 0.02

0.78 ± 0.01

0.83 ± 0.03

LVPWs (mm)

0.90 ± 0.03

1.09 ± 0.05*

0.99 ± 0.04

1.06 ± 0.04

  1. IVSd, interventricular septum depth at end diastole; IVSs, interventricular septum depth at end systole; HR, heart rate; bpm, beats per minute; LVIDs, left ventricular internal dimension at end systole; LVIDd, left ventricular internal diameter at end diastole; LVESV, left ventricular end systolic volume; LVEDV, left ventricular end diastolic volume; LVSV, left ventricular stroke volume; LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; CO, cardiac output; LVPWd, left ventricular posterior wall depth at end diastole; LVPWs, left ventricular posterior wall depth at end systole. *P < 0.05 versus control subjects. #P < 0.05 versus Hcy (n = 4).
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