Table 1 Characteristics of 18,902 participants in NHANES between 1999 and 2018.

From: Association between liver fibrosis scores and cardiovascular disease in elderly based on NHANES 1999–2018

Characteristic

Overall, N = 18,9021

N0, N = 14,6811

CVD

  

Yes, N = 4,2211

Stat

p-value2

Sex

   

93.5386033

< 0.001

Female

9,446 (50%)

7,614 (52%)

1,832 (43%)

  

Male

9,456 (50%)

7,067 (48%)

2,389 (57%)

  

Age (years)

69.64 (7.00)

68.91 (6.84)

72.20 (6.95)

-27.1665497

< 0.001

Race

   

156.7656640

< 0.001

Mexican American

1,615 (8.5%)

1,327 (9.0%)

288 (6.8%)

  

Others

3,808 (20%)

3,150 (21%)

658 (16%)

  

Non-Hispanic White

8,826 (47%)

6,516 (44%)

2,310 (55%)

  

Non-Hispanic Black

4,653 (25%)

3,688 (25%)

965 (23%)

  

Household composition

   

54.3931312

< 0.001

Married or living with a partner

10,790 (57%)

8,590 (59%)

2,200 (52%)

  

Living alone

8,112 (43%)

6,091 (41%)

2,021 (48%)

  

Education

   

265.4581861

< 0.001

Less than High School

5,752 (30%)

4,075 (28%)

1,677 (40%)

  

Completed High School

4,307 (23%)

3,326 (23%)

981 (23%)

  

More than High School

8,843 (47%)

7,280 (50%)

1,563 (37%)

  

PIR

2.54 (1.58)

2.64 (1.60)

2.19 (1.46)

17.4477176

< 0.001

BMI

28.96 (6.18)

28.73 (6.01)

29.77 (6.66)

-9.0688984

< 0.001

Smoking

   

128.6679445

< 0.001

Former

6,971 (37%)

5,183 (35%)

1,788 (42%)

  

Never

9,344 (49%)

7,582 (52%)

1,762 (42%)

  

Now

2,587 (14%)

1,916 (13%)

671 (16%)

  

Alcohol

   

2.3298775

0.13

No

6,511 (34%)

5,015 (34%)

1,496 (35%)

  

Yes

12,391 (66%)

9,666 (66%)

2,725 (65%)

  

Hypertension

   

768.6032123

< 0.001

No

7,242 (38%)

6,397 (44%)

845 (20%)

  

Yes

11,660 (62%)

8,284 (56%)

3,376 (80%)

  

Diabetes

   

495.321

< 0.001

No

14,476 (77%)

11,783 (80%)

2,693 (64%)

  

Yes

4,426 (23%)

2,898 (20%)

1,528 (36%)

  

Platelet count

227.79 (62.76)

230.18 (61.49)

219.47 (66.33)

9.398

< 0.001

ALT (U/L)

22.43 (15.81)

22.36 (14.66)

22.64 (19.28)

-0.855

0.4

AST (U/L)

25.62 (13.09)

25.33 (12.30)

26.64 (15.48)

-5.041

< 0.001

GGT (U/L)

28.69 (34.48)

27.94 (31.18)

31.29 (44.01)

-4.627

< 0.001

Alkaline phosphatase (U/L)

73.13 (31.40)

72.74 (32.41)

74.47 (27.56)

-3.453

< 0.001

Cholesterol (mg/dL)

192.81 (43.86)

197.63 (42.12)

176.04 (45.63)

27.548

< 0.001

Triglycerides (mg/dL)

153.36 (102.15)

151.98 (101.29)

158.18 (104.94)

-3.412

< 0.001

Total bilirubin (mg/dL)

0.71 (0.27)

0.70 (0.26)

0.74 (0.32)

-6.533

< 0.001

Hepatitis B surface antigen

   

4.705

0.030

Negative

18,801 (99.5%)

14,593 (99.4%)

4,208 (99.7%)

  

Positive

101 (0.5%)

88 (0.6%)

13 (0.3%)

  

eGFR

76.10 (61.06, 89.94)

79.21 (64.58, 91.40)

65.73 (50.37, 81.92)

33.018

< 0.001

FS

5.25 (4.41, 6.14)

5.11 (4.28, 5.97)

5.86 (4.97, 6.71)

21,280,625.500

< 0.001

NFS

-0.50 (-1.34, 0.40)

-0.67 (-1.44, 0.21)

0.10 (-0.87, 1.05)

21,513,908.000

< 0.001

FIB.4

1.66 (1.30, 2.13)

1.60 (1.27, 2.06)

1.87 (1.45, 2.39)

24,331,999.000

< 0.001

BARD

2.00 (1.35, 2.42)

1.93 (1.31, 2.33)

2.18 (1.61, 2.83)

24,334,659.000

< 0.001

  1. [1]n (%); Mean (SD); Median (IQR).
  2. [2]Pearson’s Chi-squared test; Welch Two Sample t-test; Wilcoxon rank sum test.
  3. PIR: Ratio of family income to poverty; ALT: Alanine aminotransferase; AST: Asparate aminotransferase; GGT: Gamma glutamyl transferase; FS: Forns Score; NFS: NAFLD Fibrosis Score; FIB.4: FIB-4 Index for Liver Fibrosis; BARD: BARD Score for Non-Alcoholic Liver Disease.
Back to article page