Table 1 Baseline Characteristics.

From: Investigation of the impact of choroidal capillary flow area on macular ischemia in diabetic patients

Parameter

Control (n = 46)

Non-DMI (n = 59)

DMI (n = 54)

P value

Gender (male/female)†

16/30

46/13

33/21

0.014

Age (year)‡

52(47.25, 59)

55(46, 63)

56(49, 62)

0.41

Duration of DM (year)§

N/A

2(1, 9)

8(1, 13)

0.04

BCVA (LogMAR)§

N/A

0.1(0, 0.1)

0.1(0, 0.2)

 < 0.001

Hb1Ac (mg/dl)§

N/A

9.300(7,400, 11.400)

9.45(7.725, 11.400)

 < 0.001

CCFA (μm2)‡

2.119(2.073, 2.196)

2.072(1.995, 2.158)

1.945(1.752, 2.063)

 < 0.001

FAZ-A (mm2)‡

0.364(0.274, 0.42)

0.287(0.239, 0.37)

0.373(0.24, 0.456)

0.023

FAZ-P (μm)‡

2.441(2.063, 2.601)

2.224(1.962, 2.46)

2.487(2.069, 2.807)

0.02

FAZ-CI‡

0.793(0.758, 0.814)

0.756(0.715, 0.813)

0.738(0.699, 0.779)

 < 0.001

SCP‡

SCP (whole) (%)

48.25(46.475, 50.1)

46.9(44.4, 48.3)

44.75(41.85, 46.9)

 < 0.001

SCP (fovea) (%)

14.25(11.625, 18.9)

15.7(12.8, 19.6)

13.4(9.7, 18.325)

0.082

SCP (parafovea) (%)

51.85(50.075, 52.9)

49.7(47.3, 51.4)

47.95(43.425, 50.2)

 < 0.001

DCP‡

DCP (whole) (%)

53.25(51.875, 55.025)

51.1(48.7, 53.1)

50.1(44.475, 52.35)

 < 0.001

DCP (fovea) (%)

29.75(24.175, 34.425)

31.5(26.5, 35.5)

27.45(22.15, 31.3)

0.009

DCP (parafovea) (%)

55.3(54.275, 57.3)

53.5(50.6, 55.7)

52.2(46.575, 54.725)

 < 0.001

Inner retinal thickness (μm)‡

40(35.75, 47)

44(39, 47)

40(36, 49)

0.26

Outer retinal thickness (μm)‡

198.5(193, 208)

203(195, 209)

203(191, 215)

0.24

Scan quality‡

8.5(8, 9)

8(8, 9)

8(7, 9)

0.313

  1. BCVA best corrected visual acuity, HbA1c glycosylated hemoglobin, CCFA choroidal capillary flow area, FAZ-A foveal avascular zone area, FAZ-P foveal avascular zone perimeter, FAZ-CI foveal avascular zone circularity index, DCP deep capillary plexus; SCP superficial capillary plexus.
  2. †Categorical variables were compared using the Chi-square test. ‡Continuous variables are presented as median (interquartile range) and were compared using the Kruskal–Wallis H test. § Comparisons of parameters between the Non-DMI and DMI groups were performed using the Mann–Whitney U test. P values < 0.05 were considered statistically significant. Bold values indicate statistically significant differences.
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