Table 3 Mixed effects model analysis of eGFR change from baseline by cumulative NSAIDs Exposure.

From: Renal safety of Long-Term Non-steroidal Anti-inflammatory drugs use in patients with ankylosing spondylitis

Years

Source

N

Estimated GFR CKD−EPI

Estimated GFR MDRD

β

95% CI

β

95% CI

3

AMC

1,224

−0.005

−0.022, 0.012

−0.010

−0.036, 0.017

SNUBH

679

0.015

−0.006, 0.036

0.009

−0.026, 0.045

Summary

1,903

0.004

−0.016, 0.023

−0.003

−0.024, 0.019

6

AMC

1,224

−0.007

−0.027, 0.014

−0.010

−0.044, 0.023

SNUBH

679

−0.016

−0.045, 0.012

−0.026

−0.074, 0.021

Summary

1,903

−0.010

−0.027, 0.007

−0.016

−0.043, 0.012

9

AMC

1,224

−0.001

−0.027, 0.024

−0.004

−0.045, 0.038

SNUBH

679

−0.051

−0.092, −0.011

−0.061

−0.127, 0.006

Summary

1,903

−0.024

−0.072, 0.025

−0.026

−0.080, 0.029

12

AMC

1,224

0.014

−0.017, 0.046

0.048

−0.002, 0.099

SNUBH

679

−0.025

−0.104, 0.054

0.035

−0.095, 0.165

Summary

1,903

0.009

−0.020, 0.038

0.046

−0.001, 0.093

15

AMC

1,224

0.002

−0.043, 0.046

0.002

−0.070, 0.074

SNUBH

679

−0.076

−0.206, 0.054

−0.186

−0.399, 0.027

Summary

1,903

−0.012

−0.070, 0.046

−0.064

−0.240, 0.112

18

AMC

1,224

−0.089

−0.159, −0.019

−0.096

−0.208, 0.017