Fig. 6
From: RDM1 plays an oncogenic role in clear cell renal cell carcinoma potentially by modulating MCM2
RDM1 expression is positively associated with MCM2 in ccRCC patients. (A) Tissue samples were obtained from surgical resections for ccRCC, and RT-qPCR was used to quantify MCM2 mRNA expression (n = 36). Student´s t‑test. n.s., not significant. (B) RT-qPCR analysis to determine the correlation between RDM1 and MCM2. Spearman´s correlation analysis. (C) Representative images of the RDM1 and MCM2 IHC staining of human ccRCC tissues from different patients. Scale bars, 100 μm. (D) Quantification of RDM1 and MCM2 protein levels. Chi-squared test. *p < 0.05. (E) RDM1 and MCM2 IHC scores were used, and patient OS was examined through log-rank test. *p < 0.05.
