Table 2 Binding affinity measurement and Units.
From: QKDTI A quantum kernel based machine learning model for drug target interaction prediction
Score | Dataset(s) | Meaning | Units |
|---|---|---|---|
Kd | DAVIS, BindingDB | Dissociation constant which measures binding strength. | nM, µM, mM |
IC50 | BindingDB | The concentration needed to inhibit 50% of the target activity. | nM, µM, mM |
Ki | BindingDB | The inhibition constant represents enzyme inhibitor binding strength. | nM, µM, mM |
KIBA Score | KIBA | Composite bioactivity score integrated from Kd, IC50, Ki, etc. | Arbitrary unit |
