Table 2 Comparison of clinical characteristics between patients with high/ low Trim24.

From: Clinical diagnostic value of serum Trim24 in patients with atherosclerosis

Variables

High Trim24 (n = 68)

Low Trim24 (n = 69)

t/Z or χ2

p value*

Age (y)

69.50 (43 ~ 88, 12)

66 (40 ~ 91, 13)

−2.103

0.036

Sex, female (%)

27 (39.71)

30 (43.48)

0.293

0.589

BMI (kg/m2)

28.65 (15.20 ~ 34.66, 7.17)

27.56 (18.30 ~ 35.20, 7.20)

−1.238

0.216

TC (mmol/L)

4.66 (2.03 ~ 9.89, 1.58)

3.84 (1.54 ~ 7.12, 2.33)

−1.950

0.051

TG (mmol/L)

1.47 (0.43 ~ 5.89, 1.43)

1.40 (0.52 ~ 7.09, 1.20)

−0.026

0.979

HDL-C (mmol/L)

1.15 (0.53 ~ 2.13, 0.37)

1.08 (0.48 ~ 1.79, 0.39)

−1.399

0.162

LDL-C (mmol/L)

2.94 (0.62 ~ 7.26, 1.31)

2.31 (0.09 ~ 5.18, 1.93)

−2.133

0.033

ALT (U/L)

15.03 (1.80 ~ 51.79, 10.00)

15.50 (5.40 ~ 50.90, 14.40)

−0.194

0.846

AST (U/L)

18.20 (8.90 ~ 39.14, 9.11)

18.80 (9.50 ~ 39.10, 8.55)

−0.204

0.838

EGFR (mL/min/1.73 m2)

104.36 (90.52 ~ 122.91, 13.83)

104.62 (90.15 ~ 137.51, 13.38)

−0.011

0.991

WBC (×109/L)

7.78 (4.23 ~ 14.89, 2.96)

7.27 (3.90 ~ 12.72, 2.68)

−1.716

0.086

hs-CRP (mg/L)

6.48 (0.29 ~ 17.13, 5.32)

6.39 (0.19 ~ 19.16, 4.73)

−0.327

0.744

FIB (g/L)

3.26 (2.24 ~ 7.19, 0.92)

3.20 (2.28 ~ 6.66, 1.02)

−0.820

0.412

HCY (µmol/L)

17.20 (5.36 ~ 29.48, 12.29)

13.09 (5.21 ~ 29.78, 8.63)

−2.495

0.013

Current smoker, n (%)

30 (44.12)

27 (39.13)

0.512

0.474

Current alcohol consumer, n (%)

3 (4.41)

10 (14.49)

5.937

0.015

Stroke, n (%)

7 (10.29)

8 (11.59)

0.087

0.768

Myocardial infraction, n (%)

11 (16.18)

14 (20.29)

0.566

0.452

Hypertension, n (%)

50 (73.53)

47 (68.12)

0.708

0.400

Diabetes, n (%)

30 (44.12)

24 (34.78)

1.826

1.177

IMT (mm)

 Left

1.06 (0.70 ~ 1.45, 0.23)

1.10 (0.60 ~ 1.50, 0.25)

−0.439

0.660

 Right

1.00 (0.60 ~ 1.49, 0.21)

1.05 (0.60 ~ 1.50, 0.28)

−0.167

0.867

 Severe AS, n (%)

60 (88.24)

34 (49.28)

35.331

< 0.001

 Severe stenosis (%)

65 (95.59)

44 (63.77)

31.268

< 0.001

  1. BMI body mass index, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine aminotransferase, AST aspartate aminotransferase, eGFR estimated glomerular filtration rate, WBC white blood cell, hs-CRP high-sensitivity C-reactive protein, FIB fibrinogen, HCY homocysteine, IMT intima-media thickness.
  2. P value was calculated using independent t-test or Mann-Whitney U test for normally or non-normally distributed data, respectively. Chi-square test was used for analysis of rates.
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