Table 1 Demographic and clinical data in parkinson’s disease (PD) patients divided into those with high levels of mood + chronic fatigue syndrome (CFS) symptoms (High MOOD + CFS) and those with lower MOOD + CFS symptoms, and healthy controls (HC).

From: Affective and chronic fatigue symptoms are associated with serum neuronal damage markers in Parkinson’s disease

Variables

Controls A

n = 60

PD; Low MOOD + CFS B

n = 40

PD; High MOOD + CFS C

n = 30

F/χ2

df

p

Age Yrs

62.5 ± 5.0

61.3 ± 11.1

65.0 ± 10.1

1.59

2/127

0.207

Sex Female/Male

19/41

15/25

9/21

0.54

2

0.765

Employment No/Yes

49/11

34/6

24/6

0.33

2

0.850

Rural/Urban ratio

19/41

11/29

12/18

1.25

2

0.536

Single/Married

1/59

1/39

0/30

FET

-

1.000

Education Yrs

9.4 ± 4.2

8.7 ± 4.7

9.7 ± 3.6

0.62

2/127

0.542

Duration of Disease Yrs

-

4.58 ± 3.07

4.40 ± 4.06

0.05

1/68

0.829

Age of onset Yrs

-

57.0 ± 11.5

62.2 ± 12.3

3.35

1/68

0.072

Family history No/Yes

60/0

33/7

29/1

FET

-

0.001

TUD No/Yes

46/14

32/8

21/9

0.96

2

0.619

BMI kg/m2

27.69 ± 4.64

28.35 ± 3.30

27.46 ± 3.16

0.52

2/127

0.598

nM-EDL

0 B, C

10.95 ± 2.94 A, C

23.27 ± 6.16 A, B

KWT

-

< 0.001

m-EDL

0 B, C

23.43 ± 10.49 A

24.37 ± 9.59 A

KWT

-

< 0.001

Part III

0 B, C

60.25 ± 24.94 A, C

69.77 ± 28.46 A, B

KWT

-

< 0.001

Part IV

0 B, C

11.78 ± 6.49 A

12.30 ± 6.67 A

KWT

-

< 0.001

MOOD

0 B, C

6.88 ± 1.73 A, C

12.32 ± 2.49 A, B

KWT

-

< 0.001

CFS

0 B, C

5.45 ± 2.06 A, C

12.37 ± 3.73 A, B

KWT

-

< 0.001

MOOD + CFS

0 B, C

9.90 ± 2.55 A, C

19.97 ± 4.41 A, B

KWT

-

< 0.001

  1. A, B, C: Significant pairwise comparisons (p < 0.05). Results are shown as means (SD). FET: Fisher exact test, KWT: Kruskal-Wallis test.
  2. BMI: body mass index, TUD: tobacco use disorder, m-EDL: Motor aspects of Experiences Daily Living, nM-EDL: Non-motor-EDL, Part III: motor examination score, Part IV: motor complications score. MOOD: mood symptoms of the nM-EDL; CFS: CFS symptoms of the nm-EDL; MOOD + CFS: sum of all MOOD and CSF symptoms.