Table 1 Comparison of baseline characteristics before and after propensity score matching.

From: Survival benefit of postoperative chemotherapy in stage III lung squamous cell carcinoma based on SEER database analysis through propensity score matching

Variables

 

Unmatched

Matched

 

Level

Non-Chemo

Chemo

P-value

Non-Chemo

Chemo

P-value

Number

 

619

1165

 

492

492

 

Age (median [IQR])

 

72.000 [66.000, 77.000]

67.000 [60.000, 72.000]

< 0.0001

72.000 [65.000, 77.000]

69.000 [63.000, 73.000]

< 0.0001

Age level (%)

< 60

53 (8.56)

279 (23.95)

< 0.0001

50 (10.16)

50 (10.16)

1

 

≥ 60

566 (91.44)

886 (76.05)

 

442 (89.84)

442 (89.84)

 

Sex (%)

Female

221 (35.70)

381 (32.70)

0.2215

175 (35.57)

172 (34.96)

0.8938

 

Male

398 (64.30)

784 (67.30)

 

317 (64.43)

320 (65.04)

 

Race (%)

White

537 (86.75)

984 (84.46)

0.3947

426 (86.59)

416 (84.55)

0.6626

 

Black

53 (8.56)

112 (9.61)

 

39 (7.93)

45 (9.15)

 
 

Others

29 (4.68)

69 (5.92)

 

27 (5.49)

31 (6.30)

 

Marital status (%)

Unmarried

67 (10.82)

148 (12.70)

0.0323

58 (11.79)

57 (11.59)

0.8226

 

Married

358 (57.84)

718 (61.63)

 

288 (58.54)

280 (56.91)

 
 

W/D/S

194 (31.34)

299 (25.67)

 

146 (29.67)

155 (31.50)

 

Primary site (%)

Upper lobe

303 (48.95)

677 (58.11)

0.0001

252 (51.22)

263 (53.46)

0.8695

 

Lower lobe

226 (36.51)

386 (33.13)

 

186 (37.80)

177 (35.98)

 
 

Middle lobe

28 (4.52)

41 (3.52)

 

20 (4.07)

17 (3.46)

 
 

Others

62 (10.02)

61 (5.24)

 

34 (6.91)

35 (7.11)

 

Laterality (%)

Left

263 (42.49)

553 (47.47)

0.05

223 (45.33)

231 (46.95)

0.6544

 

Right

356 (57.51)

612 (52.53)

 

269 (54.67)

261 (53.05)

 

Grade (%)

I

15 (2.42)

21 (1.80)

0.239

8 (1.63)

9 (1.83)

0.9244

 

II

250 (40.39)

470 (40.34)

 

194 (39.43)

194 (39.43)

 
 

III

345 (55.74)

667 (57.25)

 

286 (58.13)

283 (57.52)

 
 

IV

9 (1.45)

7 (0.60)

 

4 (0.81)

6 (1.22)

 

Tumor size (%)

≤ 3 cm

186 (30.05)

265 (22.75)

0.0001

126 (25.61)

134 (27.24)

0.8836

 

> 7 cm

137 (22.13)

249 (21.37)

 

122 (24.80)

114 (23.17)

 
 

3–5 cm

193 (31.18)

363 (31.16)

 

152 (30.89)

148 (30.08)

 
 

5–7 cm

103 (16.64)

288 (24.72)

 

92 (18.70)

96 (19.51)

 

T stage (%)

T1

55 (8.89)

119 (10.21)

< 0.0001

45 (9.15)

49 (9.96)

0.8105

 

T2

123 (19.87)

351 (30.13)

 

118 (23.98)

119 (24.19)

 
 

T3

216 (34.89)

415 (35.62)

 

186 (37.80)

194 (39.43)

 
 

T4

225 (36.35)

280 (24.03)

 

143 (29.07)

130 (26.42)

 

N stage (%)

N0

163 (26.33)

117 (10.04)

< 0.0001

83 (16.87)

71 (14.43)

0.7701

 

N1

188 (30.37)

305 (26.18)

 

162 (32.93)

165 (33.54)

 
 

N2

259 (41.84)

722 (61.97)

 

239 (48.58)

248 (50.41)

 
 

N3

9 (1.45)

21 (1.80)

 

8 (1.63)

8 (1.63)

 

Surgery methods (%)

Resection of lobe or bilobectomy

369 (59.61)

781 (67.04)

0.0001

313 (63.62)

319 (64.84)

0.9106

 

Others

124 (20.03)

148 (12.70)

 

74 (15.04)

70 (14.23)

 
 

Pneumonectomy

126 (20.36)

236 (20.26)

 

105 (21.34)

103 (20.93)

 

Radiation therapy (%)

No

531 (85.78)

541 (46.44)

< 0.0001

404 (82.11)

403 (81.91)

1

 

Yes

88 (14.22)

624 (53.56)

 

88 (17.89)

89 (18.09)

 
  1. Note: W/D/S: Widowed/Divorced/Separated.