Table 2 POMS2 TMD (total mood disturbance) scores and subscores after the Uchida-Kraepelin (U-K) test at 8 weeks and its change from baseline.
Placebo | YRC3780 | |||
|---|---|---|---|---|
Baseline | Week 8 | Baseline | Week 8 | |
TMD score after U-K test | 60.9 ± 10.3 | 53.2 ± 10.8 | 60.3 ± 11.6 | 50.0 ± 9.7 * |
Change in score from baseline (points) | — | –7.7 ± 6.0 | — | –10.4 ± 9.0 * |
Percentage change from baseline (%) | — | –12.6 ± 9.7 | — | –16.2 ± 12.5 |
AH score difference after U-K test | 57.0 ± 11.3 | 50.5 ± 11.3 | 54.9 ± 11.9 | 47.0 ± 9.3 |
Change in score from baseline (points) | — | –6.5 ± 10.8 | — | –7.9 ± 11.0 |
Percentage change from baseline (%) | — | –10.0 ± 18.8 | — | –12.5 ± 16.5 |
CB score difference after U-K test | 61.2 ± 12.4 | 53.8 ± 12.1 | 62.2 ± 12.6 | 51.9 ± 10.7 |
Change in score from baseline (points) | — | –7.4 ± 5.8 | — | –10.3 ± 10.4 |
Percentage change from baseline (%) | — | –11.9 ± 8.9 | — | –15.3 ± 14.1 |
DD score difference after U-K test | 58.9 ± 11.7 | 51.8 ± 10.4 | 57.6 ± 12.2 | 48.7 ± 9.3 |
Change in score from baseline (points) | — | –7.1 ± 6.9 | — | –8.9 ± 9.5 |
Percentage change from baseline (%) | — | –11.2 ± 11.1 | — | –14.0 ± 13.9 |
FI score difference after U-K test | 62.1 ± 9.3 | 53.7 ± 11.0 | 61.3 ± 10.9 | 51.1 ± 11.4 |
Change in score from baseline (points) | — | –8.4 ± 7.6 | — | –10.2 ± 10.1 |
Percentage change from baseline (%) | — | –13.5 ± 12.4 | — | –15.9 ± 14.6 |
TA score difference after U-K test | 59.7 ± 10.5 | 51.7 ± 10.7 | 59.8 ± 11.5 | 49.9 ± 10.5 |
Change in score from baseline (points) | — | –8.1 ± 7.2 | — | –9.9 ± 9.2 |
Percentage change from baseline (%) | — | –13.1 ± 11.7 | — | –15.8 ± 13.8 |
VA score difference after U-K test | 45.2 ± 9.1 | 45.7 ± 9.6 | 45.0 ± 9.0 | 47.3 ± 9.2 |
Change in score from baseline (points) | — | 0.5 ± 7.2 | — | 2.2 ± 7.9 |
Percentage change from baseline (%) | — | 2.1 ± 15.7 | — | 6.6 ± 16.9 |
F score difference after U-K test | 46.8 ± 10.8 | 45.2 ± 11.3 | 43.2 ± 11.2 | 44.2 ± 10.4 |
Change in score from baseline (points) | — | –1.6 ± 8.6 | — | 1.1 ± 9.3 |
Percentage change from baseline (%) | — | –2.0 ± 18.0 | — | 5.5 ± 21.8 |
