Fig. 5

Exercise activated the effects of IGF1 by reducing the serum IGFBP5/IGF1 ratio, consequently triggering the IRS1/Akt/AMPK signaling pathway to ameliorate HFD-induced NAFLD.

Exercise activated the effects of IGF1 by reducing the serum IGFBP5/IGF1 ratio, consequently triggering the IRS1/Akt/AMPK signaling pathway to ameliorate HFD-induced NAFLD.