Fig. 5 | Scientific Reports

Fig. 5

From: Integrative bioinformatics frameworks for abdominal aortic aneurysm using GWAS meta-analysis, biological network construction, and structural modeling

Fig. 5

Tissue-specific expression analysis was performed using GTEx v8. The figures were generated and visualized using the FUMA web-based platform29. (A) A bar plot illustrates the significance levels across 53 tissue types, represented on the x-axis, as determined by MAGMA. The y-axis represents the negative logarithm of the adjusted p-value (–log₁₀ adjusted p-value). The adjusted p-value was obtained using the Bonferroni correction method. (B) A heatmap displaying the average gene expression levels (logarithmically base 2 transformed), with hierarchical clustering of the 83 mapped genes across GTEx v8 54 tissue types, generated using the GENE2FUNC mode in FUMA. The red and blue color spectrum represents the high and low expression, respectively.

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