Table 3 Key proteins identified from the PPI network analysis.

From: Integrative bioinformatics frameworks for abdominal aortic aneurysm using GWAS meta-analysis, biological network construction, and structural modeling

Protein

Degree

Betweenness centrality

Essentiality

PSMA4

0.883

0.036

Hub

CD40

1.000

0.075

Hub, bottleneck

PSMC3

1.000

0.122

Hub

LRP1

1.000

0.122

Hub, bottleneck

SCARA3

1.000

0.044

Hub

MRC2

1.000

0.016

Hub

PSRC1

0.815

0.114

Bottleneck

ADAMTS7

0.825

0.123

Bottleneck

FGF9

0.614

0.214

Bottleneck

MAP2K5

0.480

0.164

Bottleneck