Table 5 The association of average retinal nerve fiber layer thickness with studied variables according to simple and multiple generalized estimating equations models.
From: Retinal nerve fiber layer thickness profile in an Iranian adult population
Simple | Multiple | |||
|---|---|---|---|---|
Coefficient (95%CI) | p-value | Coefficient (95%CI) | p-value | |
Female sex | 1.73 (0.02; 3.44) | 0.048 | 1.4 (− 0.28; 3.08) | 0.103 |
Age | ||||
50–54 | 0 | – | 0 | – |
55–59 | 1.41 (− 0.34; 3.16) | 0.115 | 1.48 (− 0.20; 3.16) | 0.085 |
60–64 | 0.19 (− 1.60; 1.99) | 0.833 | 1.04 (− 0.69; 2.76) | 0.240 |
65–69 | − 0.54 (− 2.51; 1.43) | 0.590 | 0.24 (− 1.64; 2.11) | 0.803 |
70–74 | − 3.05 (− 5.40; − 0.70) | 0.011 | − 1.12 (− 3.39; 1.16) | 0.336 |
Interaction sex and age | ||||
Female (50–54) | 0 | – | 0 | – |
Female (55–59) | − 2.34 (− 4.58; − 0.10) | 0.041 | − 1.78 (− 3.93; 0.37) | 0.105 |
Female (60–64) | − 0.54 (− 2.87; 1.79) | 0.651 | − 0.58 (− 2.81; 1.66) | 0.614 |
Female (65–69) | 1.17 (− 1.47; 3.81) | 0.386 | 0.87 (− 1.65; 3.38) | 0.500 |
Female (70–74) | 3.92 (0.65; 7.19) | 0.019 | 3.15 (0.00; 6.29) | 0.050 |
Height (cm) | − 0.01 (− 0.05; 0.03) | 0.628 | NR | |
Weight (kg) | 0.03 (0.00; 0.06) | 0.066 | NR | |
Body mass index | 0.09 (0.01; 0.17) | 0.037 | 0.11 (0.02; 0.19) | 0.013 |
Smoking (yes/no) | − 2.17 (− 5.00; 0.65) | 0.131 | NR | |
Hypertension (yes/no) | − 0.71 (− 1.53; 0.11) | 0.089 | NR | |
Diabetic (yes/no) | − 0.63 (− 1.49; 0.24) | 0.155 | − 1.09 (− 1.91; − 0.27) | 0.009 |
Systolic blood pressure (mm/Hg) | − 0.02 (− 0.04; 0.01) | 0.159 | NR | |
Diastolic blood pressure (mm/Hg) | − 0.03 (− 0.06; 0.01) | 0.149 | NR | |
Cataract surgery (Yes/No) | 0.2 (− 0.97; 1.38) | 0.737 | NR | |
Intraocular pressure (mm/Hg) | − 0.07 (− 0.17; 0.03) | 0.177 | NR | |
Axial length (mm) | − 1.78 (− 2.24; − 1.32) | < 0.001 | − 2.29 (− 2.84; − 1.74) | < 0.001 |
Central corneal thickness (microns) | 0.00 (− 0.02; 0.01) | 0.519 | NR | |
Anterior chamber depth (mm) | − 0.43 (− 1.02; 0.17) | 0.162 | NR | |
Lens thickness (mm) | 1.19 (0.00; 2.37) | 0.049 | NR | |
Corneal diameter (mm) | 0.09 (− 0.72; 0.89) | 0.835 | NR | |
Mean keratometry (diopter) | − 0.74 (− 2.22; 0.74) | 0.325 | 5.27 (3.58; 6.96) | < 0.001 |
Triglyceride (mg/dL) | 0.00 (0.00; 0.01) | 0.294 | NR | |
Total cholesterol (mg/dL) | 0.01 (0.00; 0.02) | 0.073 | NR | |
HDL cholesterol (mg/dL) | 0.03 (− 0.02; 0.09) | 0.225 | NR | |
Cardiovascular disease (Yes/No) | − 0.7 (− 1.75; 0.35) | 0.192 | NR | |
Central macular thickness (microns) | 23.3 (11.22; 35.38) | < 0.001 | − 21.39 (− 35.05; − 7.73) | 0.002 |
Macular Volume (mm3) | 7.64 (6.94; 8.34) | < 0.001 | 8.30 (7.47; 9.13) | < 0.001 |
Refractive errors | 0 | – | NR | |
Myopia | − 1.37 (− 2.05; − 0.68) | < 0.001 | ||
Hyperopia | 0.87 (0.29; 1.44) | 0.003 | ||
