Table 2 Linear regression analysis for the associations between anthropometric indices and Phenotypic Age Acceleration, weighted.

From: Associations between anthropometric indices and biological age acceleration in American adults: insights from NHANES 2009–2018 data

 

Phenotypic age acceleration

Model 1

Model 2

Model 3

β (95% CI)

p-value

β (95% CI)

p-value

β (95% CI)

p-value

ABSI

Continuous

106.71 (94.51, 118.91)

 < 0.001

114.08 (100.41, 127.75)

 < 0.001

53.31 (40.40, 66.21)

 < 0.001

R2 (cont. model)

 

0.013

 

0.096

 

0.224

Categories

Quartiles 1

Reference

Reference

Reference

Quartiles 2

0.18 (0.02, 0.34)

0.026

0.13 (-0.03, 0.28)

0.105

0.002 (-0.14, 0.15)

0.983

Quartiles 3

0.65 (0.48, 0.81)

 < 0.001

0.62 (0.46, 0.78)

 < 0.001

0.25 (0.10, 0.40)

0.001

Quartiles 4

1.40 (1.24, 1.57)

 < 0.001

1.44 (1.26, 1.62)

 < 0.001

0.71 (0.54, 0.88)

 < 0.001

p for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

R2 (quartile model)

 

0.014

 

0.098

 

0.224

BRI

Continuous

0.52 (0.49, 0.54)

 < 0.001

0.60 (0.57, 0.62)

 < 0.001

0.46 (0.43, 0.48)

 < 0.001

R2 (cont. model)

 

0.072

 

0.175

 

0.268

Categories

Quartiles 1

Reference

Reference

Reference

Quartiles 2

0.52 (0.37, 0.68)

 < 0.001

0.54 (0.39, 0.69)

 < 0.001

0.50 (0.35, 0.64)

 < 0.001

Quartiles 3

1.41 (1.26, 1.57)

 < 0.001

1.50 (1.35, 1.66)

 < 0.001

1.22 (1.07, 1.36)

 < 0.001

Quartiles 4

2.94 (2.79, 3.10)

 < 0.001

3.38 (3.22, 3.54)

 < 0.001

2.52 (2.37, 2.68)

 < 0.001

p for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

R2 (quartile model)

 

0.061

 

0.161

 

0.258

BMI

Continuous

0.18 (0.17, 0.19)

 < 0.001

0.19 (0.18, 0.19)

 < 0.001

0.15 (0.14, 1.16)

 < 0.001

R2 (cont. model)

 

0.080

 

0.164

 

0.266

Categories

Quartiles 1

Reference

Reference

Reference

Quartiles 2

0.68 (0.53, 0.84)

 < 0.001

0.34 (0.19, 0.49)

 < 0.001

0.32 (0.18, 0.47)

 < 0.001

Quartiles 3

1.56 (1.40, 1.72)

 < 0.001

1.19 (1.03, 1.34)

 < 0.001

0.97 (0.83, 1.12)

 < 0.001

Quartiles 4

3.04 (2.88, 3.20)

 < 0.001

2.91 (2.76, 3.06)

 < 0.001

2.24 (2.10, 2.39)

 < 0.001

p for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

R2 (quartile model)

 

0.065

 

0.148

 

0.255

C index

Continuous

11.98 (11.36, 12.60)

 < 0.001

13.55 (12.89, 14.22)

 < 0.001

9.26 (8.61, 9.91)

 < 0.001

R2 (cont. model)

 

0.060

 

0.145

 

0.247

Categories

Quartiles 1

Reference

Reference

Reference

Quartiles 2

0.41 (0.26, 0.57)

 < 0.001

0.55 (0.40, 0.70)

 < 0.001

0.43 (0.28, 0.57)

 < 0.001

Quartiles 3

1.24 (1.08, 1.40)

 < 0.001

1.39 (1.23, 1.55)

 < 0.001

0.97 (0.82, 1.13)

 < 0.001

Quartiles 4

2.88 (2.73, 3.04)

 < 0.001

3.13 (2.96, 3.30)

 < 0.001

2.16 (2.00, 2.33)

 < 0.001

p for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

R2 (quartile model)

 

0.060

 

0.143

 

0.246

  1. Model 1 was crude model. Model 2 was adjusted for age + sex + race. Model 3 was adjusted for Model 2 + alcohol consumption + smoking status + dietary caloric intake + physical activity + CVD + hypertension + diabetes + cancer. ABSI A Body Shape Index, BRI Body Roundness Index, BMI Body mass index, C-index Conicity Index.
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