Table 5 Detection performance and health economic evaluation of four DS screening strategies.
Project | Strategy 1 | Strategy 2 | Strategy 3 | Strategy 4 |
|---|---|---|---|---|
Total screening | 23,136 | 23,136 | 23,136 | 10,423 |
Number of true positives (effect) | 15 | 17 | 15 | 5 |
Number of people at high-risk for FTSS | 1649 | 1649 | 1649 | / |
Number of persons at critical-risk | / | 3152 | / | / |
Number of people at high risk of NIPT | / | 2 | 17 | 9 |
Number of abnormal prenatal diagnoses | 17 | 19 | 17 | 5 |
Number of induced abortions | 17 | 19 | 17 | 5 |
Number of DS misses | 4 | 2 | 4 | 1 |
Total cost (CNY) | 28,597,700 | 21,297,900 | 29,184,500 | 20,480,300 |
Cost per capita (CNY) | 1236.08 | 920.51 | 1261.43 | 1964.91 |
CER (CNY) | 1,906,500 | 1,252,800 | 1,945,600 | 4,096,100 |
