Fig. 3 | Scientific Reports

Fig. 3

From: Nuclear localization and upregulation of BAI1 in alveolar macrophages during LPS-Induced acute lung injury

Fig. 3

BAI1 is immunoreactive in adult mouse lungs and elevated in ALI mouse lungs. (A, B) Representative photomicrographs of lung tissues stained with hematoxylin and eosin (H&E) were obtained, and a large inflammatory cell infiltrate was observed in the lung of ALI mice. (C, D, E) Immunohistochemistry on adjacent paraffin sections using the antibody PA5-75348. In the lungs of normal adult mice, BAI1 was mainly expressed in the nuclei of AMs, but was relatively weak in the cytoplasm of airway epithelial cells. Moreover, BAI1 expression increased with the elevation of AMs in the lung tissues of mice with ALI. (F, G) Immunofluorescence staining of lung tissues showed BAI1 immunoreactivity mainly originated from a small number of AMs in the alveolar cavity. Scale bars: A, B, C, D, E, F = 100 μm.

Back to article page