Table 1 eQTL GWAS MR Analysis of the top 50 genes in HCC.

From: Multi-omics analysis identifies SNP-associated immune-related signatures by integrating Mendelian randomization and machine learning in hepatocellular carcinoma

Exposure

Outcome

Method

Nsnp

Pval

OR

WDR18

HCC

IVW

3

0.037071997

2.28611551

CYB5D1

HCC

IVW

3

0.012870151

2.142247373

ARL8A

HCC

IVW

3

0.049222391

2.081530166

DDAH2

HCC

IVW

3

0.046411129

2.07066307

ATG2A

HCC

IVW

3

0.007724044

1.990741837

SDF2L1

HCC

IVW

4

0.005797678

1.949172158

TRAV26-2

HCC

IVW

3

4.56E-05

1.929009673

SNTG2

HCC

IVW

3

0.002441823

1.858338087

SLC16A3

HCC

IVW

3

0.011538826

1.802519589

SLC2A3

HCC

IVW

3

0.042938508

1.747689684

HSPA5

HCC

IVW

6

0.000860017

1.699377168

NFE2L2

HCC

IVW

4

0.022165286

1.680937199

MSL3

HCC

IVW

3

0.042942243

1.632070088

ADRB2

HCC

IVW

3

0.003919286

1.602655324

CHD4

HCC

IVW

3

0.020745311

1.598676254

KIR3DL2

HCC

IVW

4

0.025105636

1.592984455

MDS2

HCC

IVW

3

0.014819259

1.588688716

C1RL

HCC

IVW

6

0.027507484

1.587988344

ZNF827

HCC

IVW

3

0.028913374

1.580950884

PLIN5

HCC

IVW

5

0.03896345

1.574656053

ADIRF

HCC

IVW

3

0.022725054

1.560990048

HEXA

HCC

IVW

3

0.001348939

1.545797651

STK40

HCC

IVW

5

0.031333583

1.525215808

NT5DC4

HCC

IVW

3

0.031882438

1.516745851

ATP13A1

HCC

IVW

5

5.12E-07

1.49396323

RARA-AS1

HCC

IVW

3

0.018046744

1.47355705

PARP9

HCC

IVW

6

0.035469575

1.460987438

CSNK2A2

HCC

IVW

3

0.043227124

1.448641414

STRBP

HCC

IVW

5

0.03271822

1.44520639

CDK11B

HCC

IVW

3

0.036644733

1.423368293

GTF3C3

HCC

IVW

3

0.023932225

1.411544377

IRAK4

HCC

IVW

3

0.017108893

1.396014908

CR1

HCC

IVW

5

0.01912396

1.383637677

H2BC11

HCC

IVW

5

0.023650421

1.381163692

ACACB

HCC

IVW

5

0.003291001

1.380278285

USP10

HCC

IVW

4

0.019849766

1.37059153

NOTCH4

HCC

IVW

3

0.00175231

1.365560547

LPAR2

HCC

IVW

12

0.000211656

1.357590371

ATP10D

HCC

IVW

5

0.018103338

1.342487046

RUVBL1

HCC

IVW

3

0.029255488

1.341301512

ARHGEF35

HCC

IVW

3

0.024388754

1.323113279

MAP3K13

HCC

IVW

3

0.015274577

1.315254793

RIPK3

HCC

IVW

4

0.03567233

1.303498442

BSCL2

HCC

IVW

7

0.028778496

1.292904266

C5orf67

HCC

IVW

3

0.046742339

1.292280389

CCNJL

HCC

IVW

11

0.022875167

1.292193913

SLC25A4

HCC

IVW

5

0.02401652

1.290982553

FLVCR2

HCC

IVW

5

0.028223355

1.286562895

GABARAPL2

HCC

IVW

5

0.01014781

1.281935642

HBP1

HCC

IVW

3

0.042085321

1.280514549

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