Fig. 4 | Scientific Reports

Fig. 4

From: Liver developmental microenvironment promotes iHSC generation from human iPSCs

Fig. 4

Novel critical biomarkers of HSCs and the validation. a, UMAP plot showing the relative positions of HSCs compared to other hepatic cells. b, HSC-related marker genes were selected by integration of single cell RNA sequencing data from different astrocytes. c, UMAP expression plot of 8 novel HSC-specific marker genes. d, qRT-PCR analysis of novel HSC-specific marker genes. Results are presented as the mean ± standard deviation (SD) from three independent experiments. ns indicates no significant difference. *p < 0.05, **p < 0.01, *** p < 0.001, **** p < 0.0001.

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